SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18
Guangming Su, Wei Yang, Shengjiao Wang, Chunhui Geng, Xiuru Guan
Topics & Concepts
AutophagyFoam cellChemistryGPX4Western blotReactive oxygen speciesMacrophageCell biologyProgrammed cell deathCellMolecular biologyBiochemistryBiologyApoptosisAntioxidantCatalaseGeneIn vitroGlutathione peroxidaseFerroptosis and cancer prognosisClusterin in disease pathologyImmune cells in cancer