Aluminum Amidinates: Insights into Alkyne Hydroboration
Katie Hobson, Claire J. Carmalt, Clare Bakewell
Abstract
), which can then proceed to catalyze the reaction. This mechanism is in contrast to previously reported aluminum hydride-catalyzed hydroboration reactions, which are proposed to proceed via the initial formation of an aluminum acetylide, or by hydroalumination to form a vinylboronate ester as the first step in the catalytic cycle.
Topics & Concepts
HydroborationChemistryBoraneAlkyneBoranesReaction mechanismHydrideCatalysisMedicinal chemistryStereochemistryOrganic chemistryHydrogenBoronOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisCatalytic Cross-Coupling Reactions