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Aspergillus terreus Species Complex

Cornelia Lass-Flörl, Anna-Maria Dietl, Dimitrios P. Kontoyiannis, Matthias Brock

2021Clinical Microbiology Reviews81 citationsDOIOpen Access PDF

Abstract

Infections due to Aspergillus species are an acute threat to human health; members of the Aspergillus section Fumigati are the most frequently occurring agents, but depending on the local epidemiology, representatives of section Terrei or section Flavi are the second or third most important. Aspergillus terreus species complex is of great interest, as it is usually amphotericin B resistant and displays notable differences in immune interactions in comparison to Aspergillus fumigatus . The latest epidemiological surveys show an increased incidence of A. terreus as well as an expanding clinical spectrum (chronic infections) and new groups of at-risk patients being affected.

Topics & Concepts

Species complexAspergillusAspergillus terreusBiologyAmphotericin BEpidemiologyIncidence (geometry)Immune systemPathogenesisImmunologyMicrobiologyMedicineBridge (graph theory)AspergillosisMycotoxinKey (lock)Computational biologyAntifungal resistance and susceptibilityFungal Infections and StudiesOcular Infections and Treatments
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