Phase 2a Study of Baxdrostat in Primary Aldosteronism
Adina F. Turcu, Mason W. Freeman, Irina Bancos, Anat Ben-Shlomo, Oksana Hamidi, Amir H. Hamrahian, Wenyu Huang, Lawrence S. Kirschner, Ramin Sam, Ashwini Mallappa, Bonifride Tuyishimire, Aina Sætre Lihn, Shira Perl, Morris J. Brown
Abstract
In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone prod...
Topics & Concepts
Primary aldosteronismPrimary (astronomy)Phase (matter)HyperaldosteronismMedicineAldosteroneInternal medicineChemistryPhysicsOrganic chemistryAstronomyHormonal Regulation and HypertensionAdrenal and Paraganglionic TumorsEicosanoids and Hypertension Pharmacology