Litcius/Paper detail

BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells

Paolo Mita, Xiaoji Sun, David Fenyö, David J. Kahler, Donghui Li, Neta Agmon, Aleksandra Wudzinska, Sarah Keegan, Joel S. Bader, Chi Young Yun, Jef D. Boeke

2020Nature Structural & Molecular Biology115 citationsDOIOpen Access PDF

Topics & Concepts

RetrotransposonBiologyHomologous recombinationDNA repairUbiquitin ligaseDNACell biologyGeneticsReplication protein AFanconi anemiaDNA replicationDNA damageGenome instabilityUbiquitinGeneDNA-binding proteinTranscription factorGenomeTransposable elementChromosomal and Genetic VariationsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques