A case of multisystem inflammatory syndrome (MIS-A) in an adult woman 18 days after COVID-19 vaccination
Sofie Stappers, Britt Ceuleers, Daan Van Brusselen, Philippe Willems, Brecht De Tavernier, Anke Verlinden
Abstract
We discuss a case of a young woman, presenting a constellation of clinical and biochemical features meeting the current case definition of multisystem inflammatory syndrome in adults (MIS-A), 18 days after receiving her first dose of the Oxford/AstraZeneca vaccine. Therapy by means of intravenous immunoglobulins was initiated, leading to clinical and biochemical recovery. Although a relationship between MIS-A and the preceding vaccination cannot be confirmed, it can also not be excluded, given the temporal association and the fact that there were no indicators of a preceding SARS-CoV-2 infection.
Topics & Concepts
MedicineVaccinationCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPediatricsImmunologyInternal medicinePathologyOutbreakDiseaseInfectious disease (medical specialty)Kawasaki Disease and Coronary ComplicationsSARS-CoV-2 and COVID-19 ResearchHeparin-Induced Thrombocytopenia and Thrombosis