Membrane Interactions of Virus-like Mesoporous Silica Nanoparticles
Sara Malekkhaiat Häffner, Elisa Parra‐Ortiz, Kathryn L. Browning, Elin Jørgensen, Maximilian W. A. Skoda, Costanza Montis, Xiaomin Li, Debora Berti, Dongyuan Zhao, Martin Malmsten
Abstract
bacteria. Taken together, these findings demonstrate that topography influences the interaction of nanoparticles with bacteria-mimicking lipid bilayers, both in the absence and presence of antimicrobial peptides, as well as with bacteria. The results also identify virus-like mesoporous nanoparticles as being of interest in the design of nanoparticles as delivery systems for antimicrobial peptides.
Topics & Concepts
Mesoporous silicaNanoparticleLipid bilayerNeutron reflectometryMembraneBiophysicsMaterials scienceBilayerNanotechnologyMesoporous materialChemistryChemical engineeringSmall-angle neutron scatteringNeutron scatteringBiochemistryScatteringBiologyPhysicsOpticsCatalysisEngineeringBacteriophages and microbial interactionsAntimicrobial Peptides and ActivitiesBacterial Infections and Vaccines