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Enhancing lignocellulosic biorefinery sustainability: mechanisms and optimization of microwave-responsive deep eutectic solvents for rapid delignification

Huan Wang, Jiasheng Chen, Zhengfei Pei, Jinshu Huang, Junqi Wang, Song Yang, Hu Li

2025Biofuel Research Journal46 citationsDOIOpen Access PDF

Abstract

Attaining sustainability and carbon neutrality necessitates a transition towards cleaner biorefinery, while the exploitation of sustainable and eco-friendly pretreatment techniques, as a pivotal stage in lignocellulose biorefinery, represents a challenge. Here, an ultrafast biomass pretreatment strategy enabled by microwave (MW) responsive deep eutectic solvent (DES) is proposed. The solvent properties (Kamlet-Taft parameters) of DES under MW participation are closely correlated with wheat straw fractionation efficiency. The lignin removal exhibits a positive correlation with polarity/polarizability (π*) and hydrogen-bond-donating ability (α), establishing a strong relationship between the tunable DES properties and MW responsiveness. MW reinforces the delignification efficiency of DES with relatively high π* and α, as corroborated by comparative analysis with conventional heating (CH) pretreatment. The reinforcement by MW moderates the pretreatment process and enables ultrafast lignocellulose deconstruction (130 ℃, 150 s, and 96.1% lignin removal), subsequently with 92.4% enzymatic hydrolysis and 8.8 g microbial lipid/100 g wheat straw at a remarkably low severity factor (R0). Life cycle assessment manifests the environmental benefits of MW-assisted DES in mitigating impacts by 63.1%, including global warming potential, resource depletion-fossil fuels, and ecotoxicity, in comparison to CH pretreatment. MW-DES exhibits an economic superiority based on life cycle cost analysis, with pretreatment cost 44.1% lower than CH-DES. The mechanistic insights into MW intensification of DES with specific properties provide a viable protocol for tailoring green solvents with enhanced MW responsiveness for efficient and sustainable biorefineries.

Topics & Concepts

BiorefinerySustainabilityLignocellulosic biomassDeep eutectic solventEutectic systemPulp and paper industryBiochemical engineeringChemistryBiofuelWaste managementEngineeringOrganic chemistryBiologyEcologyAlloyBiofuel production and bioconversion
Enhancing lignocellulosic biorefinery sustainability: mechanisms and optimization of microwave-responsive deep eutectic solvents for rapid delignification | Litcius