Persistent Anti- <i>Borrelia</i> IgM Antibodies without Lyme Borreliosis in the Clinical and Immunological Context
Mateusz Markowicz, Michael Reiter, Jutta Gamper, Gerold Stanek, Hannes Stockinger
Abstract
The reactivity of human IgM with the outer surface protein C (OspC) of Borrelia burgdorferi sensu lato is frequently used to detect Borrelia specific IgM in commercial immunoassays, and such antibodies usually occur in the early phase of the infection. We identified a group of individuals with persistent Borrelia IgM without symptoms of Lyme borreliosis.
Topics & Concepts
Borrelia burgdorferiSerologyImmunologyAntibodyBorreliaErythema chronicum migransAntigenImmunoglobulin MLyme diseaseSpirochaetaceaeVirologyContext (archaeology)Erythema migransLyme borreliosisMedicineBiologySensuEtiologySerotypeImmunoglobulin GAntibody responseLYMESyphilisMicrobiologyVector-borne infectious diseasesBrucella: diagnosis, epidemiology, treatmentBartonella species infections research