Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A
Brian Long, P. Véron, Klaudia Kuranda, Romain Hardet, Nina Mitchell, Gregory M. Hayes, Wing Yen Wong, Kelly Lau, Mingjin Li, M. Benjamin Hock, Stephen J. Zoog, Christian Vettermann, Federico Mingozzi, Becky Schweighardt
Topics & Concepts
ImmunogenicityImmunologyImmune systemMedicineGenetic enhancementAdeno-associated virusAntibodyPeripheral blood mononuclear cellVirologyVector (molecular biology)BiologyRecombinant DNAGeneIn vitroBiochemistryVirus-based gene therapy researchCAR-T cell therapy researchHemophilia Treatment and Research