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Leveraging LD eigenvalue regression to improve the estimation of SNP heritability and confounding inflation

Shuang Song, Wei Jiang, Yiliang Zhang, Lin Hou, Hongyu Zhao

2022The American Journal of Human Genetics28 citationsDOIOpen Access PDF

Topics & Concepts

ConfoundingHeritabilityStatisticsRegressionEconometricsEstimationInflation (cosmology)MathematicsRegression analysisSNPBiologyGeneticsEconomicsSingle-nucleotide polymorphismGenotypeManagementGeneTheoretical physicsPhysicsGenetic Associations and EpidemiologyCancer-related molecular mechanisms researchRNA modifications and cancer
Leveraging LD eigenvalue regression to improve the estimation of SNP heritability and confounding inflation | Litcius