Synthesis of chalcogen-functionalized 4<i>H</i>-chromen-4-ones <i>via</i> cyclization/chalcogenation of alkynyl aryl ketones mediated by Selectfluor®
Thiago Anjos, Elba L. Gutterres, Daniela A. Barancelli, Roberta Cargnelutti, Benhur Godoi, Thiago Barcellos, Ricardo F. Schumacher
Abstract
The selective 6- endo-dig cyclization reaction of alkynyl aryl ketones with electrophilic organochalcogen species in the presence of Selectfluor® is described.
Topics & Concepts
ChemistrySelectfluorChalcogenArylMedicinal chemistryOrganic chemistryCombinatorial chemistryStereochemistryCatalysisAlkylOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesOrganic Chemistry Cycloaddition Reactions