Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
Melitini Koutsoviti, Angeliki Siamidi, Panagoula Pavlou, Marilena Vlachou
Abstract
In ocular drug delivery, maintaining an efficient concentration of the drug in the target area for a sufficient period of time is a challenging task. There is a pressing need for the development of effective strategies for drug delivery to the eye using recent advances in material sciences and novel approaches to drug delivery. This review summarizes the important aspects of ocular drug delivery and the factors affecting drug absorption in the eye including encapsulating excipients (chitosan, hyaluronic acid, poloxamer, PLGA, PVCL-PVA-PEG, cetalkonium chloride, and gelatin) for modified drug delivery.
Topics & Concepts
Drug deliveryDrugHyaluronic acidGelatinChitosanPharmacologyBiomedical engineeringNanotechnologyMedicineMaterials scienceChemistryOrganic chemistryAnatomyAdvanced Drug Delivery SystemsOcular Surface and Contact LensNanoparticle-Based Drug Delivery