Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with <i>N</i>-Tosylhydrazones
Shivashankar Kattela, Carlos Roque D. Correia, Abel Ros, Valentı́n Hornillos, Javier Iglesias‐Sigüenza, Rosario Fernández, José M. Lassaletta
Abstract
-alkylation of the products allowed us to obtain appealing functionalized axially chiral heterobiaryl derivatives.
Topics & Concepts
ChemistryRacemizationPhosphoramiditeCatalysisLigand (biochemistry)Kinetic energyKetoneCoupling reactionCombinatorial chemistryCoupling (piping)AlkylationEnantioselective synthesisOrganic chemistryEngineeringDNAOligonucleotideQuantum mechanicsBiochemistryPhysicsReceptorMechanical engineeringAxial and Atropisomeric Chirality SynthesisAlkaloids: synthesis and pharmacologyMolecular spectroscopy and chirality