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Mild chronic hypoxia-induced HIF-2α interacts with c-MYC through competition with HIF-1α to induce hepatocellular carcinoma cell proliferation

Han Mu, Yu Ge, Huikai Li, Mengmeng Wang, Yunlong Cui, Ti Zhang, Tianqiang Song, Changfu Liu

2021Cellular Oncology19 citationsDOIOpen Access PDF

Topics & Concepts

Hypoxia (environmental)Hepatocellular carcinomaCell growthCancer researchCompetition (biology)MedicineInternal medicineOncologyChemistryBiologyBiochemistryOxygenEcologyOrganic chemistryCancer, Hypoxia, and MetabolismAngiogenesis and VEGF in CancerMechanisms of cancer metastasis