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Electrochemical C–H Functionalization for the Construction of C–O Bonds: A Comprehensive Review

Chen Liu, Renxiu Zhang, Yunge Liu, Yunfei Zhang

2025Chinese Journal of Chemistry10 citationsDOI

Abstract

Comprehensive Summary The topic of C–H functionalization and C–O formation is the most important area in organic synthesis. Traditional methods are very limited due to the necessary external oxidants, whereas the rapidly developing electrochemical synthesis uses electrons as internal redox reagents. Consequently, electrochemical C–H functionalization for the construction of C–O bonds has emerged as an active area of research. This review categorizes recent reports on the electrochemical formation of C–O bonds with various C–H sources based on the hybridization (sp 3 , sp 2 ) of the carbon atoms involved. Potential readers will gain a more comprehensive understanding of advances in the field through this review. Key Scientists

Topics & Concepts

ChemistrySurface modificationElectrochemistryCombinatorial chemistryNanotechnologyElectrodePhysical chemistryMaterials scienceCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsCO2 Reduction Techniques and Catalysts
Electrochemical C–H Functionalization for the Construction of C–O Bonds: A Comprehensive Review | Litcius