Litcius/Paper detail

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia

Gretchen Johnston, Haley E. Ramsey, Qi Liu, Jing Wang, Kristy R. Stengel, Shilpa Sampathi, Pankaj Acharya, Maria P. Arrate, Matthew C. Stubbs, Timothy C. Burn, Michael R. Savona, Scott W. Hiebert

2020Gene47 citationsDOIOpen Access PDF

Topics & Concepts

BiologyMyeloid leukemiaCancer researchProgenitor cellMyeloidChromatinLeukemiaTranscriptomeAzacitidineStem cellTranscription factorGene expressionGeneMolecular biologyCell biologyGeneticsDNA methylationEpigenetics and DNA MethylationAcute Myeloid Leukemia ResearchImmune cells in cancer