LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-145 inhibition in gastric cancer
Haiyan Piao, Shuai Guo, Haoyi Jin, Yue Wang, Jun Zhang
Abstract
Our findings indicate that the LINC00184/miR-145/ANGPT2 pathway has a crucial function in the development of GC and can act as a possible biomarker and targets for GC therapy.
Topics & Concepts
Competing endogenous RNACancermicroRNABiologyCancer researchMedicineGeneGeneticsDownregulation and upregulationLong non-coding RNACancer-related molecular mechanisms researchRNA modifications and cancerRNA Research and Splicing