UV C Light from a Light-Emitting Diode at 275 Nanometers Shortens Wound Healing Time in Bacterium- and Fungus-Infected Skin in Mice
Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Yufeng Li, Feng Yun, Rongqian Wu
Abstract
therapy using UVC light. It is well known that prolonged exposure to UVC light increases the possibility of skin cancer. In addition, it is also very harmful for eyes. UV irradiation with 254-nm UVC light can cause corneal damage, like thinning of the corneal epithelial layer, superficial punctate keratitis, corneal erosion, etc. In this study, we focused on looking for a more accessible light source and safer UVC wavelength, and 275-nm UVC LED light was chosen. We investigated its applicability for SSTIs therapy with relative skin safety and expected that it could be used as a new physical therapy method for SSTIs.
Topics & Concepts
MicrobiologyStaphylococcus aureusAntimicrobialIn vivoCandida albicansWound healingAntibioticsPathogenic bacteriaBacteriaBiologyMedicineImmunologyGeneticsBiotechnologyAntifungal resistance and susceptibilityPhotodynamic Therapy Research StudiesLaser Applications in Dentistry and Medicine