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Nuclear Export Inhibitors Selinexor (KPT-330) and Eltanexor (KPT-8602) Provide a Novel Therapy to Reduce Tumor Growth by Induction of PANoptosis

Samuel Camilli, Richard F. Lockey, Narasaiah Kolliputi

2023Cell Biochemistry and Biophysics24 citationsDOI

Topics & Concepts

PyroptosisNecroptosisInflammasomeCell biologyProgrammed cell deathCancer researchNuclear export signalApoptosisProtein kinase ACell growthBiologyChemistryKinaseReceptorBiochemistryCytoplasmCell nucleusinterferon and immune responsesInflammasome and immune disordersNuclear Structure and Function
Nuclear Export Inhibitors Selinexor (KPT-330) and Eltanexor (KPT-8602) Provide a Novel Therapy to Reduce Tumor Growth by Induction of PANoptosis | Litcius