Metal nanoparticles in neuroinflammation: impact on microglial dynamics and CNS function
Masood Alaei, Khadijeh Koushki, Kimia Taebi, Mahdieh Yousefi Taba, Samaneh Keshavarz Hedayati, Sanaz Keshavarz Shahbaz
Abstract
NPs) in modulating microglial activity. Some NPs promote anti-inflammatory effects, while others exacerbate neuroinflammation. We examine how these NPs influence microglial activation, focusing on their potential therapeutic benefits and risks. A deeper understanding of NP-microglia interactions is crucial for developing safe and efficient treatments for neuroinflammatory and neurodegenerative disorders.
Topics & Concepts
NeuroinflammationMicrogliaMetalChemistryDual roleNanoparticleBiophysicsFunction (biology)NanotechnologyMaterials scienceCell biologyInflammationMedicineImmunologyCombinatorial chemistryBiologyOrganic chemistryNeuroinflammation and Neurodegeneration MechanismsGinger and Zingiberaceae researchAdvanced Nanomaterials in Catalysis