Domestically Acquired NDM-1–Producing <i>Pseudomonas aeruginosa</i>, Southern California, USA, 2023
Hannah K. Gray, Omer E. Beaird, Ethan A. Smith, Joanna Schaenman, Shangxin Yang
Abstract
We describe a case of New Delhi metallo-β-lactamase 1-producing carbapenem-resistant Pseudomonas aeruginosa (CRPA) in a transplant patient with multiple hospitalizations in California, USA. Whole-genome sequencing revealed the isolate was genetically distinctive, despite ≈95% similarity to other global strains. The patient's lack of international travel suggests this CRPA was acquired domestically.
Topics & Concepts
Pseudomonas aeruginosaNew delhiWhole genome sequencingMicrobiologyMobile genetic elementsBiologyGenomeBacteriaMedicineGeneticsGeneMetropolitan areaPathologyAntibiotic Resistance in BacteriaAntibiotic Use and ResistanceAntibiotics Pharmacokinetics and Efficacy