Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro
Li Tang, Feixia Wang, Lingyan Xiao, Min Shen, Siwei Xia, Zili Zhang, Feng Zhang, Shizhong Zheng, Shanzhong Tan
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BHepatocyteApoptosisLiver injuryLY294002PharmacologyDownregulation and upregulationIn vivoSignal transductionMedicineCancer researchIn vitroBiologyChemistryCell biologyBiochemistryBiotechnologyGeneDrug-Induced Hepatotoxicity and ProtectionLiver Disease and TransplantationLiver physiology and pathology