N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation
Jie Du, Wang Liao, Weicheng Liu, Dilip K. Deb, Lei He, Phillip J. Hsu, Tivoli Nguyen, Linda Zhang, Marc Bissonnette, Chuan He, Yan Chun Li
Topics & Concepts
BiologySuppressor of cytokine signaling 1TLR4MacrophageMethylationCell biologyCytokineCancer researchImmunologySignal transductionIn vitroGeneSuppressorGeneticsRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation