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The identification of a CD47-blocking “hotspot” and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination

Rui Shi, Yan Chai, Xiaomin Duan, Xiaoshan Bi, Qingrui Huang, Qihui Wang, Shuguang Tan, George F. Gao, Jianhua Zhu, Jinghua Yan

2020Signal Transduction and Targeted Therapy30 citationsDOIOpen Access PDF

Topics & Concepts

AntibodyHemagglutinationBlocking (statistics)CD47ImmunologyVirologyBiologyComputer scienceComputer networkPhagocytosis and Immune RegulationErythrocyte Function and PathophysiologyImmune cells in cancer
The identification of a CD47-blocking “hotspot” and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination | Litcius