Silver nanoparticles induce endothelial cytotoxicity through ROS-mediated mitochondria-lysosome damage and autophagy perturbation: The protective role of N-acetylcysteine
Jing He, Yunyun Ma, Xudong Niu, Jiansheng Pei, Ru Yan, Fangjing Xu, Jing Ma, MA Xiao-juan, Shaobin Jia, Wanrui Ma
Topics & Concepts
AutophagyMitophagyReactive oxygen speciesLysosomeCell biologyCytotoxicityMitochondrionChemistryApoptosisAcetylcysteineProgrammed cell deathUmbilical veinMitochondrial ROSCell damageBiologyBiochemistryIn vitroAntioxidantEnzymeNanoparticles: synthesis and applicationsAutophagy in Disease and TherapyHeavy Metal Exposure and Toxicity