Cocrystallization of the anticancer drug 5-fluorouracil and coformers urea, thiourea or pyrazinamide using supercritical CO2 as an antisolvent (SAS) and as a solvent (CSS)
Isaac A. Cuadra, Albertina Cabañas, J.A.R. Cheda, Michael Türk, Concepción Pando
Topics & Concepts
Supercritical fluidDifferential scanning calorimetryThioureaMethanolChemistryPowder diffractionNuclear chemistrySolventUreaFourier transform infrared spectroscopyMaterials scienceOrganic chemistryChemical engineeringCrystallographyEngineeringPhysicsThermodynamicsCancer Treatment and PharmacologyCrystallography and molecular interactionsSynthesis of β-Lactam Compounds