Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis
Yajun Cui, Weidong Zhang, Panpan Yang, Siqi Zhu, Sheng-Lei Luo, Minqi Li
Topics & Concepts
OsteoblastOsteonecrosis of the jawApoptosisBone remodelingBone healingOxidative stressCell biologyOsteoclastCancer researchChemistrySirtuin 1PharmacologyMedicineBisphosphonateEndocrinologyBiologyDownregulation and upregulationBiochemistryOsteoporosisIn vitroSurgeryGeneBone health and treatmentsBone and Joint DiseasesRetinoids in leukemia and cellular processes