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Nanonewton forces between <i>Staphylococcus aureus</i> surface protein IsdB and vitronectin

Marion Mathelié‐Guinlet, Felipe Viela, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne

2020Nanoscale Advances11 citationsDOIOpen Access PDF

Abstract

. In line with this, flow experiments show that IsdB-mediated bacterial adhesion to Vn is enhanced by fluid shear stress. The stress-dependent binding of IsdB to Vn is likely to play a role in promoting bacterial adhesion to human cells under fluid shear stress conditions.

Topics & Concepts

Staphylococcus aureusVitronectinMicrobiologySurface proteinChemistryBiologyBacteriaGeneticsBiochemistryVirologyIntegrinCellBiochemical and Structural CharacterizationForce Microscopy Techniques and ApplicationsBacterial biofilms and quorum sensing