Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China
Mengyuan Dai, Zhen Chen, Yan Leng, Meng Wu, Yu Liu, Fuxiang Zhou, Ming Chen, Ning‐Yi Shao, Miao Liu, Hongbing Cai
Abstract
Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.