Establishment of human intestinal organoids derived from commercially available cryopreserved intestinal epithelium and evaluation for pharmacokinetic study
Kentaro Okada, Jumpei Yokota, Tomoki Yamashita, Tatsuya Inui, Wataru Kishimoto, Hiroshi Nakase, Hiroyuki Mizuguchi
Topics & Concepts
OrganoidPharmacokineticsIntestinal epitheliumCYP3A4Small intestineCYP3ABiologyChemistryMolecular biologyCell biologyEpitheliumPharmacologyCytochrome P450BiochemistryEnzymeGeneticsCancer Cells and Metastasis3D Printing in Biomedical ResearchChemical Reactions and Isotopes