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Topologically associating domain boundaries that are stable across diverse cell types are evolutionarily constrained and enriched for heritability

Evonne McArthur, John A. Capra

2021The American Journal of Human Genetics212 citationsDOIOpen Access PDF

Topics & Concepts

HeritabilityDomain (mathematical analysis)Evolutionary biologyBiologyComputational biologyMathematicsMathematical analysisGenomics and Chromatin DynamicsSingle-cell and spatial transcriptomicsCell Image Analysis Techniques
Topologically associating domain boundaries that are stable across diverse cell types are evolutionarily constrained and enriched for heritability | Litcius