Phenylboronic acid-functionalized polyaminoglycoside as an effective CRISPR/Cas9 delivery system
Meiyu Shao, Yu Qi, Dandan Sui, Fu‐Jian Xu
Abstract
, suggesting the potential of PBA-functionalized nanocarriers for cancer gene therapy. The present work provides a promising approach for the treatment of malignant tumors.
Topics & Concepts
CRISPRPhenylboronic acidChemistryDelivery systemComputer scienceComputational biologyBiologyBiochemistryPharmacologyGeneCatalysisCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques