Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons
Alena Kozlova, Siwei Zhang, Alex Kotlar, Brendan Jamison, Hanwen Zhang, Serena Qinyun Z. Shi, Marc P. Forrest, John McDaid, David J. Cutler, Michael P. Epstein, Michael E. Zwick, Zhiping P. Pang, Alan R. Sanders, Stephen T. Warren, Pablo V. Gejman, Jennifer G. Mullé, Jubao Duan
Topics & Concepts
BiologyPhenotypeLoss functionGeneticsInduced pluripotent stem cellMutationSynapseCopy-number variationGeneTranscriptomeNeuroscienceGene expressionGenomeEmbryonic stem cellGenetics and Neurodevelopmental DisordersGenomic variations and chromosomal abnormalitiesChromosomal and Genetic Variations