Design, synthesis and evaluation of flurbiprofen-clioquinol hybrids as multitarget-directed ligands against Alzheimer’s disease
Ziyi Yang, Qing Song, Zhongcheng Cao, Guangjun Yu, Zhuoling Liu, Zhenghuai Tan, Yong Deng
Topics & Concepts
ClioquinolChemistryFlurbiprofenPharmacologyLead compoundBiological activityAlzheimer's diseaseIn vitroBiochemistryDiseaseInternal medicineMedicineCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsComputational Drug Discovery Methods