pH-Responsive nanoplatform synergistic gas/photothermal therapy to eliminate biofilms in poly(<scp>l</scp>-lactic acid) scaffolds
Guowen Qian, Yuqian Mao, Huihui Zhao, Lemin Zhang, Long Xiong, Zhisheng Long
Abstract
under near infrared light irradiation compared with single gas or photothermal therapy. In addition, the composite scaffold promoted the proliferation and osteogenic differentiation of mouse bone marrow mesenchymal stem cells. Thus, the designed scaffold with excellent biofilm elimination and osteogenesis ability has great potential as an alternative treatment for implant-associated bone infections.
Topics & Concepts
BiofilmPhotothermal therapyLactic acidBacteriaComposite numberMaterials scienceChemical engineeringPhotothermal effectChemistryNanotechnologyComposite materialBiologyEngineeringGeneticsNanoplatforms for cancer theranosticsBone Tissue Engineering MaterialsAdvanced Nanomaterials in Catalysis