Clonogenic assay and computational modeling using real cell images to study physical enhancement and cellular sensitization induced by metal nanoparticles under MV and kV X-ray irradiation
Rodrigo Hernández Millares, Chaewon Bae, Seokjin Kim, Tae‐Wan Kim, So‐Yeon Park, Kangwon Lee, Sung‐Joon Ye
Abstract
radiation through mechanisms akin to ferroptosis inducers, not exclusively relying on a physical dose enhancement. Their own contributions to survival fractions were successfully integrated into computational modeling.
Topics & Concepts
Clonogenic assaySensitizationNanoparticleMaterials scienceColloidal goldIrradiationA549 cellNanotechnologyCellBiophysicsChemistryMedicineImmunologyBiochemistryPhysicsBiologyNuclear physicsRadiation Therapy and DosimetryAdvanced Radiotherapy TechniquesNuclear Physics and Applications