Lung ultrasound features and relationships with respiratory mechanics of evolving BPD in preterm rabbits and human neonates
Barbara Loi, Costanza Casiraghi, Chiara Catozzi, Matteo Storti, Monica Lucattelli, Barbara Bartalesi, Nadya Yousef, Fabrizio Salomone, Danièle De Luca
Abstract
We have reported that hyperoxia-exposed preterm rabbits and human preterm neonates with evolving BPD have the same lung ultrasound appearance, and that lung ultrasound can be fruitfully applied on this model with a brief training. The animal model and human neonates also presented the same relationship between semiquantitative ultrasound-assessed lung aeration and airway resistances. In conclusion, this animal model fairly reproduce evolving BPD as it is seen in clinical practice.
Topics & Concepts
Bronchopulmonary dysplasiaUltrasoundMedicineLungHyperoxiaGestational ageRespiratory systemGestationRespiratory physiologyPathologyRadiologyInternal medicinePregnancyBiologyGeneticsNeonatal Respiratory Health ResearchCongenital Diaphragmatic Hernia StudiesUltrasound in Clinical Applications