Role of cytokines and Th17/Tregs imbalance in the pathogenesis of otitis media with effusion. Modulation of Notch1/Hes1/mTORC1/S6k1 signalling pathway underlies the protective effect of astaxanthin
Noura Mostafa Mohamed, Amira Mohamed Abdelhamid, Mohamed Aref, Marwa Abdelhafeez, Hadil Faris Alotabi, Doaa Abdelrahman, Nisreen E. Elwany
Topics & Concepts
PathogenesisMedicineProinflammatory cytokinemTORC1AstaxanthinLipopolysaccharideImmunologyOtitisEndocrinologyHES1Internal medicineInflammationSignal transductionBiologyProtein kinase BReceptorNotch signaling pathwayBiochemistryCarotenoidSurgeryEar Surgery and Otitis MediaHearing, Cochlea, Tinnitus, GeneticsVestibular and auditory disorders