Litcius/Paper detail

Investigating the Effect of Lewis Acid Co-catalysts on Photosensitized Visible-Light De Mayo Reactions

Riley M. Kelch, Andrew Whyte, Eunji Lee, Tehshik P. Yoon

2023Organic Letters19 citationsDOIOpen Access PDF

Abstract

Herein, we describe studies showing that Lewis acid co-catalysts can significantly broaden the scope of alkenes that can be incorporated into the photosensitized visible-light De Mayo reaction. Mechanistic studies suggest that the primary benefit of the Lewis acid is not on substrate sensitization but rather on bond-forming steps downstream of energy transfer, highlighting the diverse effects that Lewis acids can have on sensitized photoreactions.

Topics & Concepts

ChemistryLewis acids and basesCatalysisSubstrate (aquarium)PhotochemistryLewis acid catalysisCombinatorial chemistryOrganic chemistryGeologyOceanographyRadical Photochemical ReactionsFluorine in Organic ChemistrySulfur-Based Synthesis Techniques