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Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy

Xiaohui Ma, Xiaotong Wu, Shitai Cao, Yinfeng Zhao, Yong Lin, Yurui Xu, Xinghai Ning, Desheng Kong

2023Advanced Science64 citationsDOIOpen Access PDF

Abstract

Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on-demand release of anticancer drugs under electro-thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities.

Topics & Concepts

Wearable computerWearable technologyElectronicsComputer scienceMedicineBiomedical engineeringEmbedded systemComputer hardwareElectrical engineeringEngineeringAdvanced Sensor and Energy Harvesting MaterialsNanoplatforms for cancer theranosticsNanomaterials and Printing Technologies
Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy | Litcius