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Artificial Intelligence and Its Role in Predicting Periprosthetic Joint Infections

Diana Elena Vulpe, Cătălin Anghel, Cristian Scheau, Şerban Dragosloveanu, Oana Săndulescu

2025Biomedicines11 citationsDOIOpen Access PDF

Abstract

Periprosthetic joint infections (PJIs) represent one of the most problematic complications following total joint replacement, with a significant impact on the patient's quality of life and healthcare costs. The early and accurate diagnosis of a PJI remains the key factor in the management of such cases. However, with traditional diagnostic measures and risk assessment tools, the early identification of a PJI may not always be adequate. Artificial intelligence (AI) algorithms have been integrated in most technological domains, with recent integration into healthcare, providing promising applications due to their capability of analyzing vast and complex datasets. With the development and implementation of AI algorithms, the assessment of risk factors and the prediction of certain complications have become more efficient. This review aims to not only provide an overview of the current use of AI in predicting PJIs, the exploration of the types of algorithms used, and the performance metrics reported, but also the limitations and challenges that come with implementing such tools in clinical practice.

Topics & Concepts

PeriprostheticJoint infectionsJoint (building)MedicineMicrobiologyIntensive care medicineBiologyComputer scienceArtificial intelligenceEngineeringSurgeryArthroplastyStructural engineeringOrthopedic Infections and TreatmentsOrthopaedic implants and arthroplastyArtificial Intelligence in Healthcare and Education