1,2-Diborylsilanes: Catalytic Enantioselective Synthesis and Site-Selective Cross-coupling
Ziyin Kong, Weipeng Hu, James P. Morken
Abstract
A Pt-catalyzed enantioselective hydrosilylation of ( Z )-1,2-diborylethylene provides a 1,2-diboryl-1-silylalkane that can be used in catalytic cross-coupling reactions. Depending on the catalyst employed and the cross-coupling reaction conditions, the coupling can occur at either α or β relative to the silane center.
Topics & Concepts
Enantioselective synthesisCatalysisHydrosilylationCoupling (piping)Coupling reactionChemistryCombinatorial chemistryStereochemistryOrganic chemistryMaterials scienceMetallurgyOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsRadical Photochemical Reactions