Undescribed phenylpropanoid and a dimeric sesquiterpenoid possessing a rare cyclobutane ring from <i>Tinospora sinensis</i>
Abidah Parveen, Zulfıqar Ali, Omer I. Fantoukh, Manal Alhusban, Wei Wang, Amar G. Chittiboyina, Ikhlas A. Khan
Abstract
A rare dimeric sesquiterpenoid (tinosposinoside, 1) and a phenylpropanoid (cordifolioside C, 2), two undescribed metabolites, were isolated from the methanolic extract of the stems of Tinospora sinensis together with thirteen known compounds. This is the second example of a sesquiterpene dimer where two monomers linked together through a cyclobutane ring, possibly generated through [2 + 2] cycloaddition. The structures of 1 and 2 were elucidated by NMR and mass techniques.
Topics & Concepts
CyclobutanePhenylpropanoidDimerStereochemistryChemistryRing (chemistry)SesquiterpeneCycloadditionBiosynthesisOrganic chemistryEnzymeCatalysisPhytochemicals and Medicinal PlantsMedicinal Plants and NeuroprotectionPlant biochemistry and biosynthesis