Umbelliferone ameliorates ulcerative colitis induced by acetic acid via modulation of TLR4/NF-κB-p65/iNOS and SIRT1/PPARγ signaling pathways in rats
Basel A. Abdel‐Wahab, Saad A. Alkahtani, Abdulsalam A. Alqahtani, Emad H. M. Hassanein
Topics & Concepts
TLR4Oxidative stressSignal transductionPharmacologyChemistryColitisUmbelliferoneUlcerative colitisNF-κBPeroxisome proliferator-activated receptorInflammationInflammatory bowel diseaseProinflammatory cytokinePathogenesisBiochemistryReceptorMedicineImmunologyInternal medicineCoumarinDiseaseOrganic chemistryPharmacological Effects of Natural CompoundsGenomics, phytochemicals, and oxidative stressGinseng Biological Effects and Applications