SPSiPs, a Class of Diphosphine Ligands Based on SPSiOL with a Large Dihedral Angle
Hao Li, Peng‐Gang Zhao, Caiyun Wang, Ruoyu Zhang, Jian-Jun Li, Yichen Wu, Peng Wang
Abstract
The development and the synthetic applications of a novel class of diphosphine ligands (SPSiPs) based on chiral spirosilabiindane diol (SPSiOL) are presented. Starting from SPSiOL, the diphosphine ligands could be readily prepared in three steps with high efficiency. This novel class of diphosphine ligands features rigid configuration, a large dihedral angle, a large P-M-P angle, and a long P-P distance. The potentials of SPSiPs in asymmetric catalysis have also been preliminarily disclosed.
Topics & Concepts
Dihedral angleChemistryDiolCatalysisClass (philosophy)Bite angleCombinatorial chemistryStereochemistryCrystallographyPolymer chemistryOrganic chemistryMoleculeCrystal structureComputer scienceHydrogen bondDenticityArtificial intelligenceAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and CatalysisChemical Synthesis and Analysis