A visible light-mediated three-component strategy based on the ring-opening of cyclic ethers with aryldiazoacetates and nucleophiles
Mateus L. Stivanin, Rafael D. C. Gallo, João Paulo M. Spadeto, Rodrigo A. Cormanich, Igor D. Jurberg
Abstract
A visible light-mediated strategy insensitive to air or moisture allows a 3-component reaction between aryldiazoacetates, cyclic ethers and various nucleophiles to afford formal O–H inserted products of more complex alcohols.
Topics & Concepts
ChemistryNucleophileRing (chemistry)Component (thermodynamics)Combinatorial chemistryOrganic chemistryCatalysisPhysicsThermodynamicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques