Rapid identification and pharmacokinetic studies of multiple active alkaloids in rat plasma through UPLC-Q-TOF-MS and UPLC-MS/MS after the oral administration of Zanthoxylum nitidum extract
Qiyan Lin, Hongli Pu, Huida Guan, Chao Ma, Yunpeng Zhang, Wenzheng Ding, Xuemei Cheng, Lili Ji, Zhengtao Wang, Changhong Wang
Topics & Concepts
ChemistryChromatographySanguinarinePharmacokineticsHigh-performance liquid chromatographyRadix (gastropod)Mass spectrometryDetection limitTandem mass spectrometryAlkaloidPharmacologyStereochemistryMedicineBiologyBotanyBerberine and alkaloids researchSynthesis and Biological ActivitySynthesis and bioactivity of alkaloids