Amino‐Supported Palladium Catalyst for Chemo‐ and Stereoselective Domino Reactions
Man‐Bo Li, Jie Yang, Ying Yang, Guoyong Xu, Gen Luo, Jianping Yang, Jan‐E. Bäckvall
Abstract
A solid amino-supported palladium catalyst is used in an oxidative domino reaction for the diastereoselective construction of alkyne-substituted cyclopentenol compounds. This heterogeneous catalyst exhibits high efficiency and excellent chemoselectivity, as well as good recyclability. The chemoselectivity of the domino reactions was readily controlled by switching the solvent and catalyst. Asymmetric syntheses and an oxidative carbocyclization-borylation reaction have also been developed based on the heterogeneous palladium catalyst.
Topics & Concepts
ChemoselectivityCatalysisPalladiumDominoChemistryStereoselectivityAlkyneCascade reactionCombinatorial chemistryBorylationOrganic chemistryArylAlkylCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry MethodsAsymmetric Synthesis and Catalysis