Quantitation of cystic fibrosis triple combination therapy, elexacaftor/tezacaftor/ivacaftor, in human plasma and cellular lysate
Kevin J. Ryan, Jennifer S. Guimbellot, Alexander E. Dowell, Kedria D. Reed-Walker, Corenna Kerstner-Wood, Justin D. Anderson, Zhongyu Liu, Edward P. Acosta
Topics & Concepts
ChemistryChromatographyFormic acidProtein precipitationAnalyteSelected reaction monitoringTandem mass spectrometryLiquid chromatography–mass spectrometryIvacaftorMass spectrometryBiochemistryCystic fibrosis transmembrane conductance regulatorGeneCystic Fibrosis Research AdvancesNematode management and characterization studiesLegume Nitrogen Fixing Symbiosis